WSLH Research Support Center

Experts in WSLH Research

Mei Baker, M.D., FACMG

 

Contact Information

 

Title

Education

  • MD, Department  of Medicine, Anhui Medical University, P. R. of China: 1983
  • Fellow in Clinical Biochemical Genetics, UW-Waisman Center: 2007
  • Board-certified Biochemical Geneticist, American Board of Medical Genetics: 2009

Fields of Interests

  • Application of molecular technology in  newborn screening
  • DNA-based and MS/MS screening for genetic metabolic disorders in newborns
  • Newborn screening for severe combined immunodeficiency (SCID)
  • Public health genetics

Publications

  • Routes JM, Grossman WJ, Verbsky J, Laessig RH, Hoffman GL, Brokopp CD, Baker MW. Statewide Newborn Screening for Severe T-Cell Lymphopenia. JAMA 302 (22): 2465-2470, 2009.
  • Baker MW, Grossman WJ, Laessig RH, Hoffman GL, Brokopp CD, Kurtycz DF, Cogley MF, Litsheim TJ, Katcher ML, Routes JM. Development of a routine newborn screening protocol for severe combined immunodeficiency. J Allergy Clin Immunol 124 (3): 522-7, 2009.
  • The Working Group for Newborn Screening for SCID (Baker  JC, Baker MW, et al) Puck JM. Development of population-based newborn screening for SCID.  J Allergy Clin Immunol  120 (4): 760-8, 2007.
  • Baker MW, Hoffman GL, Rice GM, Van Calcar SC, Laessig RH, Kurtycz DF, Wolff JA. Successful Early Molecular Screening of MSUD on Two At-Risk Newborns in Wisconsin Newborn Screening Program. (Abstract) J Iherit Metab Dis (2006) 29 Suppl 1. Presented as a poster at ICIEM 2006, Japan.
  • Johnson SC, Marshall DJ, Harms G, Miller CM, Sherrill CB, Beaty EL, Lederer SA, Roesch EB, Madsen G, Hoffman GL, Laessig RH, Kopish GJ, Baker MW, Benner SA, Farrell PM, Prudent JR  Multiplexed Genetic Analysis Using an Expanded  Genetic Alphabet. Clinical Chemistry. 50: 2019-2027, 2004.
  • Croen LA, Shaw GM, Barber RC, Baker MW, Finnell RH, Lammer EJ.  Apolipoprotein B and apolipoprotein E genotypes and sporadic holoprosencephaly.  American Journal of Medical Genetics 108(1):75-7, 2002.
  • Shaw GM, Lammer EJ, Zhu H, Baker MW, Neri E, Finnell RH.  Maternal periconceptional vitamin use, genetic variation of infant reduced folate carrier (A80G), and risk of spina bifida.  American Journal of Medical Genetics 108(1):1-6, 2002.
  • Susan Belleh, Guimei Zhou, Mei Wang, Vazken M. Kaloustian, Roberta A. Pagon, MauriceGodfrey.  Two Novel Fibrillin-2 Mutations in Congenital Contractural Arachnodactyly.  American Journal of Medical Genetics 92:7-12, 2000.
  • Watnick T; Phakdeekitcharoen B; Johnson A; Gandolph M; Wang M; Briefel G; Klinger KW; Kimberling W; Gabow P; Germino GG.  Mutation Detection of PKD1 Identifies a Novel Mutation Common to Three Families with Aneurysms and/or Very-Early-Onset Disease.   Am J Hum Genet 65(6): 1561-1571, 1999.
  • Julia A. Bridge, Mary E. Fidler, James R. Neff, Joanne Degenhardt, Mei Wang, Craig Walker, Howard D. Dorfman, K. Scott Baker, Thomas A. Seemayer, Adamantinoma-like Ewing’s Sarcoma:  Genetic Confirmation, Phenotypic Drift. American Journal of SurgicalPathology 23(2), 159-165, 1999.
  • Wang, M., Mathews, K., Imaizumi, K., Beiraghi, S., Blumberg, B., Scheuner, M., Graham, J., Godfrey, M.  P1148A in fibrillin-1 is not a mutation anymore.  Nature Genetics, 15:12, 1997.
  • Wang, M., Wang, J-Y., Imaizumi, K., Burton, B.K., Jones, M.C., Lamberti, J.J., and Godfrey, M.  Three novel fibrillin mutations in exons 25 and 27:  classical versus neonatal Marfan syndrome.  Human Mutation, 9:359-362, 1997.
  • Wang, M., Clericuzio, C.L., and Godfrey, M.  Familial occurrence of typical and severe lethal congenital contractural arachnodactyly caused by missplicing of exon 34.  American Journal of Human Genetics, 59 :1027-1034, 1996.
  • Wang, M., Kishnani, P., Decker-Phillips, M., Kahler, S.G., and Godfrey, M. Double mutant allele in the FBN1 gene in a case of neonatal Marfan syndrome.  J. Med. Genet. 33:760-763, 1996.
  • Wang, M., Price, C.E., Han, J., Cisler, J., Imaizumi, K., Van Thienen, M.N., De Paepe, A., and Godfrey, M.  Recurrent mis-splicing of fibrillin exon 32 in two patients with neonatal Marfan syndrome. Human Molecular Genetics, 4:607-613, 1995.
  • Wang, M., Mata, J.E., Price, C.E., Iversen, P.L., and Godfrey, M.  Prenatal and presymptomatic diagnosis of the Marfan syndrome using fluorescence PCR and an automated sequencer. PrenatalDiagnosis, 15:499-507, 1995.
  • Godfrey, M., Vandemark,  N., Wang, M., Velinov, M., Wargowski, D., Tsipouras, P., Han, J., Becker, J., Robertson, W., Droste, S., and Rao, V.H. Prenatal Diagnosis and a Donor Splice Site Mutation in Fibrillin in a Family with the Marfan syndrome. American Journal of Human Genetics, 53:472-480, 1993.

Book Chapter

  • Wang, M., and Godfrey, M.:  Prenatal and presymptomatic diagnosis of Marfan Syndrome using fluorescence PCR and an automated sequencer, PCR in Bioanalysis , Stephen J. Meltzer, M.D. (ed.), Humane Press, Totowa, N.J., pp. 49-54, 1998.

 

Contact Information

Wisconsin State Laboratory of Hygiene
Newborn Screening Laboratory
465 Henry Mall
Madison, WI 53706
Phone: 608-890-1796
Fax: 608-262-5494

E-mail: bakermw@mail.slh.wisc.edu
E-mail: mwbaker@wisc.edu

 

 

 

 

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