Deletions
| Abnormal chromosome is on the right in each pair |
Abnormality(major breakpoint or breakpoint range) |
Disorder |
||
 del(5)(q22q35) |
 del(5)(q13q33) |
del(5)(q12-q35) | AML, MDS | |
 del(6)(q21q25) |
 del(6)(q15q21) |
del(6)(q13-q27) | ALL, CLL | |
 del(7)(q11.2) |
 del(7)(q11.2q36) |
 del(7)(q22q34) |
del(7)(q11.2-q36) | AML, MDS |
 del(7)(q21q31) |
 del(7)(q22) |
 del(7)(q22) |
del(7)(q21q31), del(7)(q22) | Uterine leiomyomas, genotoxic exposures |
 del(9)(p13) |
 del(9)(p22) |
 del(9)(p21) |
del(9)(p13), del(9)(p21-p22 | ALL, malignant melanoma |
 del(9)(q13q22) |
 del(9)(q13q34) |
del(9)(q21-q22) [most common region, but deletion seen along various 9q sites] | AML (secondary changes) | |
 del(11)(p13) |
del(11)(p13) | Wilm’s tumor | ||
 del(11)(q23) |
 del(11)(q23) |
 del(11)(q13q23) |
del(11q) | MDS, B-cell Non-Hodgkin’s lymphoma |
 del(12)(p12) |
 del(12)(p12) |
del(12)(p12) | ALL, AML, MDS | |
 del(13)(q12q14) |
 del(13)(q12q21.2) |
 del(13)(q12q22) |
del(13)(q12-q34) | MPD, MDS, MM |
 del(14)(q22q31) |
 del(14)(q22q31) |
del(14)(q22q31) | Non-Hodgkin’s lymphoma | |
 del(20)(q11.2q13.1) |
 del(20)(q11.2) |
 del(20)(q11.2) |
del(20)(q11.2-q13.1), del(20)(q11.2) | AML, MDS, MPD |
 del(22)(q11.2) |
 del(22)(q11.2) |
 del(22)(q13) |
del(22) | Meningioma |
Deletions | Inversion/Isochromosome | Translocations 1 | Translocations 2
University of Wisconsin Cytogenetic Services